OVERVIEW:
The following article is about an opioid derivative known as codeine phosphate. Its indications for usage and all the aspects of this drug including the information that from where patients can buy codeine phosphate UK.
Water does not dissolve codeine (base). Codeine phosphate is very soluble, whereas Codeine Sulfate is not. I’d have to dissolve codeine (base) in alcohol to make a solution.
The base of codeine is not used in medicine. (I’ve never seen it before.)
To give therapeutic equivalencies between the different salts, we commonly refer to the equivalent weight in the base form when discussing doses of medication salts. When the weight of the base and the salts differ significantly, this is more commonly done.
For example, 400 mg of Codeine Phosphate is roughly equivalent to 300 mg of Codeine Base (or over 700 mg of the Sulfate as a trihydrate)
CODEINE PHOSPHATE:
Codeine phosphate UK is a morphine or opium derivative. It is used to treat a variety of medical conditions. Its implication is as an analgesic, a kind of antitussive agent and as an anti-diarrheal medicine.
MECHANISM OF ACTION OF CODEINE PHOSPHATE:
Codeine phosphate brings its effects by acting as a selective agonist to the opioid receptors in the brain although the rate of affinity for the mu-receptor is much less as compared to the more potent morphine drug. Mu-receptors are responsible for sensing and the transmission of the pain throughout the central nervous system and the body.
AVAILABLE FORMS OF CODEINE PHOSPHATE:
Codeine phosphate 30 mg comes in a tablet or pill form. It is in the form of white un-coated tablets. Each tablet consists of 30 milligrams of codeine phosphate hemihydrate and 16 milligrams of lactose BP.
INDICATIONS FOR USE OF CODEINE PHOSPHATE:
The therapeutic indications for which patients buy codeine phosphate UK are as following:
- It is prescribed as an analgesic to get symptomatic relief from mild to moderate intensity of pain.
- This also indicated for symptomatic relief of un-productive cough.
- The also given to the patients suffering from diarrhea.
RECMMENDED OSAGE OF CODEINE PHOSPHATE:
Codeine phosphate dosage should be kept as minimum as possible and the risk and benefit ratio should be regularly monitor by the physician and it should also be used for the shortest possible intervals. As a general guideline maximum dosage in a day should not exceed 240 milligram in a day and the dosage should be divide in such an order that it can be taken three to four times in a day with the minimum gap of 4 to 6 hours between the next dosage intake. Medication course should be continue for 3 days and if no improvement is noticed then the prescriber should be informed to treat via alternative options.
It’s like taking anxiety pills: when you first start, you only need one tablet; however, as the weeks and months pass, your body requires more and more anxiety pills to achieve the same effect.
This is the same with a codeine overdose: you could die from as little as one pack of 30mg tablets to begin with, but be warned: the death from failed attempts, in my experience, is long and painful. Your body will be itchy all over, and you’ll keep fainting and falling. You’ll be so dizzy that you’ll be pleading with the paramedics to hurry up.
DOSAGE FOR ANALGESIA:
ADULTS:
To achieve analgesia in adults the dose should be 30 to 60 milligrams every four hours till the effects are achieved. Maximum dosage is 240 milligrams.
GERIATRIC DOSE:
In elderly the dosage is relatively less. The dosage should be more clearly monitor among individuals with renal or hepatic insufficiencies.
PAEDIATRIC DOSE:
It can be use among children that are older than 12 years of age. The dosage is calculated as per the body weight with the dose of 0.5 to 1 milligram per kilograms of body weight. It is not advised to be used among children that are less than 12 years of age.
DOSAGE FOR COUGH:
ADULTS:
Adult dosage is 15 to 30 milligrams three to four times a day. It should be use carefully among elderly patients and usually dosage is reduce to half as compared to the adult dose.
DOSAGE FOR DIARRHEA:
ADULT DOSE:
Dosage for adults and children who are above 12 years is from 15 to 60 milligrams given three to four times in a day. Not recommended in children above 12 years. Should be prescribe carefully to renally and hepatically compromise geriatric patients.
CONTRAINDICATIONS:
Under certain medical condition codeine phosphate should be avoide to avoid any life-threatening complications. The condition in which codeine phosphate is contraindicated are as follows:
- Any hypersensitivity to the ingredients of the composition.
- Obstructive lung disorders
- Acute alcoholism
- Respiratory depression
- Associated risk of paralytic ileus
- Head trauma with the possibility of raised intra-cranial pressure
- Contraindicated in lactose intolerant individuals
- Not given to the individuals who are chronic alcoholics
ADVERSE EFFECTS OF CODEINE PHOSPHATE:
The most encountered dihydrocodeine adverse effects are:
- Drug dependance
- Tolerance
- Drug abuse
- Drug withdrawal symptoms
- Restlessness
- Lacrimation
- Frequent yawning
- Rhinorrhea
- Palpitations
- Mydriasis
- Perspirations
- Chills
- Myalgias
- Anxiety
- Hyperkinesia
- weakness
- tremors
- insomnia
- irritability
- anorexia
- abdominal cramping
- nausea
- vomiting
- diarrhea
- increased in blood pressure
- it respiratory rate
- increased pulse and heart rate
- if taken by pregnant mother then the newly born child may experience neonatal withdrawal symptoms.
- hyperalgesia
OPTIONS TO PURCHASE CODEINE PHOSPHATE:
Codeine phosphate was available as an over-the-counter medicine for past many years in the countries such as UK, France and Ireland. It was also available in combined form to aspirin, ibuprofen and paracetamol but now they are available only on the provision of prescription. They can be purchased from the drug stores and from online authentic websites via codeine phosphate 30 mg buy option one can opt for door step delivery. One should only use it as per the prescriber’s guidelines to ensure that the benefits outnumber the risks associated with this drug usage.
